Knutsford is a market town and civil parish in the Cheshire East district, in Cheshire, England; it is located 14 miles south-west of Manchester, …Knutsford is a market town and civil parish in the Cheshire East district, in Cheshire, England; it is located 14 miles south-west of Manchester, 9 miles north-west of Macclesfield and 12+1⁄2 miles south-east of Warrington. The population at the 2011 Census was 13,191.